Last edited by Mazugrel
Tuesday, July 21, 2020 | History

2 edition of Chiral recognition in separation methods found in the catalog.

Chiral recognition in separation methods

Alain Berthod

Chiral recognition in separation methods

mechanisms and applications

by Alain Berthod

  • 314 Want to read
  • 28 Currently reading

Published by Springer in Heidelberg, New York .
Written in English

    Subjects:
  • Biotechnology,
  • Enantiomers,
  • Molecular recognition

  • Edition Notes

    Includes bibliographical references and index.

    StatementAlain Berthod, editor
    Classifications
    LC ClassificationsQP517.M67 C48 2010
    The Physical Object
    Paginationxiv, 337 p. :
    Number of Pages337
    ID Numbers
    Open LibraryOL25148754M
    ISBN 103642124445
    ISBN 109783642124440, 9783642124457
    LC Control Number2010929210
    OCLC/WorldCa646113721

    D Other Methods of Resolution. One of the major goals in the field of organic chemistry is the development of reagents with the property of "chiral recognition" such that they can effect a clean separation of enantiomers in one operation without destroying either of the have not achieved that ideal yet, but it may not be far in the future. What drives a scientist to edit a book on a speci c scienti c subject such as chiral mechanisms in separation methods? Until December , the journal Analytical Chemistry of the American Chemical Society (Washington, DC) had an A-page section that was dedicated to simple and clear presentations of the most recent te- niques or the state of.

    Thoroughly revised, with either entirely new or completely updated contents, this is a practical manual for the small and large-scale preparation of enantiomerically pure products. The result is a vital resource for meeting the highest purity standards in the manufacture of chiral pharmaceuticals, food additives and related compounds. All the approaches covered here are . In chemistry, a molecule or ion is called chiral (/ k aɪ ˈ r æ l /) if it cannot be superposed on its mirror image by any combination of rotations and geometric property is called chirality. The terms are derived from Ancient Greek χείρ (cheir), meaning "hand"; which is the canonical example of an object with this property.. A chiral molecule or ion exists in two.

    Editorial Reviews. From the reviews of the second edition: “The second edition of Chiral Separations: Methods and Prools discusses almost every kind of chiral separation method, with the emphasis on fundamental research and experimental design. it is a very useful book for scientists and students involved in the enantioseparation field, and scientists involved in R & D . Principles Governing Chiral Separation Concept: formation of a diastereomeric complex in a chromatographic equilibrium such that the nonchiral interactions are at minimum strength and the differential chiral interaction is at maximum strength. Identifying those points of interaction between the stationary phase and the racemate guidesFile Size: 1MB.


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Chiral recognition in separation methods by Alain Berthod Download PDF EPUB FB2

A better understanding of these processes is crucial for setting as well as improving chiral separation procedures and also for developing new applications. The coverage in this book includes a range of separation methods, such as gas, liquid, or countercurrent chromatography, and capillary electrophoresis.

Chiral Recognition in Separation Methods. chiral separation procedures and also for developing new applications. The coverage in this book includes a range of Author: Alain Berthod. Chiral recognition in separation methods is a valuable book compiling a detailed description of most of the essential chiral selectors employed in chromatographic and electrophoretic techniques.

Both students and practitioners interested in enantiorecognition mechanisms should have it in their library.” (Caroline West, Analytical and Format: Hardcover. Chiral recognition in separation methods is a valuable book compiling a detailed description of most of the essential chiral selectors employed in chromatographic and electrophoretic techniques.

Both students and practitioners interested in enantiorecognition mechanisms should have it in their library.” (Caroline West, Analytical and.

Chiral recognition of racemic mixtures continues to be an active area of research in gas chromatography, liquid chromatography, and of late, capillary electrophoresis.

Whatever the separation technique employed, chiral recognition is obtained in one of three ways: 1. Formation of diastereomers 2 by additives to the mobile phase or carrier electrolyte.

Due to both practical and theoretical reasons, the properties and the possible preparation techniques of chiral compounds are investigated in ever widening fields of research, applying various examination methods [1, 2].It is a great challenge for some researchers if the goal is to find a simple, inexpensive, economical and also patentable preparation of a given chiral Author: Emese Pálovics, Szeleczky Zsolt, Szolnoki Beáta, Bosits Miklós, Fogassy Elemér.

What drives a scientist to edit a book on a speci c scienti c subject such as chiral mechanisms in separation methods.

Until Decemberthe journal Analytical Chemistry of the American Chemical Society (Washington, DC) had an A-page section that was dedicated to simple and clear presentations of the most recent te- niques or the state of the art in a Brand: Springer Berlin Heidelberg. Chiral recognition in separation methods.

Mechanisms and applications Article (PDF Available) in Analytical and Bioanalytical Chemistry (1) April with Reads.

Chiral Recognition in Separation Methods by Alain Berthod,available at Book Depository with free delivery worldwide. Get this from a library. Chiral recognition in separation methods: mechanisms and applications. [Alain Berthod;] -- The importance of chiral interactions for both preparative and analytical separations, particularly for pharmaceutical applications, is underlined by numerous publications in this field.

Here, for. This book details the mechanisms of chiral selection in separation processes. It examines the various mechanisms that result in enantiomer separations and covers a range of separation methods, such as gas, liquid, and capillary electrophoresis.

In addition, the theory of chiral separation is covered in sufficient detail to guide the practising chromatographer interested in developing new techniques.

A team of experts from academic and industrial laboratories throughout the world have compiled their findings and experience to make this book an exceptionally timely and unique.

Browse book content. About the book. Search in this book and can achieve the successful resolution of a wide range of chiral compounds particularly by optimizing the separation conditions. The chiral recognition mechanism of the polysaccharide-based CSPs has been investigated on the basis of chromatographic methods, and spectroscopic and.

adshelp[at] The ADS is operated by the Smithsonian Astrophysical Observatory under NASA Cooperative Agreement NNX16AC86ACited by: Chiral Recognition Mechanisms in Analytical Separation Sciences.

Chromatographia75 (), DOI: /s István Ilisz, Zoltán Pataj, Anita Aranyi, Antal Péter. Macrocyclic Antibiotic Selectors in Direct HPLC by: What drives a scientist to edit a book on a speci c scienti c subject such as chiral mechanisms in separation methods.

Until Decemberthe journal Analytical Chemistry of the American Chemical Society (Washington, DC) had an A-page section that was dedicated to simple and clear presentations of the most recent te- niques or the state of the art in a particular eld or : Springer Berlin Heidelberg.

Novel methods of chiral separation. Biochemistry • Chemistry. By Invited Researcher Septem 1 comment. Author: Adrián Matencio is pursuing a PhD at the Department of Biochemistry and Molecular Biology – A, Faculty of Biology, University of Murcia, where he graduated in biotechnology.

Chiral recognition in separation methods is a valuable book compiling a detailed description of most of the essential chiral selectors employed in chromatographic and electrophoretic techniques.

Both students and practitioners interested in enantiorecognition mechanisms should have it in their library.".

Abstract. Chiral recognition phenomena play an important role in nature as well as analytical separation sciences. In separation sciences such as chromatography and capillary electrophoresis, enantiospecific interactions between the enantiomers of an analyte and the chiral selector are required in order to observe by: 7.

From the reviews of the second edition: “The second edition of Chiral Separations: Methods and Protocols discusses almost every kind of chiral separation method, with the emphasis on fundamental research and experimental design.

it is a very useful book for scientists and students involved in the enantioseparation field, and scientists involved in R & D areas such as. The macrocyclic glycopeptide chiral selectors are natural molecules produced by bacterial fermentation. Purified and bonded to silica particles, they make very useful chiral stationary phases (CSP) with a broad spectrum of applicability in enantiomeric separation.

The macrocyclic glycopeptide CSPs are multimodal, the same column being able to work in normal phase Cited by: Direct methods Overviews of different chiral separation princi-ples and various applications to different com-pound classes are given in References [3–7].

Specialized reviews report on the application of different HPLC approaches to the chiral separation of various drug classes [32], NSAIDs [33], drugs possessing carboxyl groups [34], b-Cited by: Chiral recognition on a molecular level is essential for the rational design of chiral separation media and for understanding the fundamental interactions between biological molecules.

It is especially important in all of the life chemistries, particularly in pharmacology, due to the differences in behavior between the enantiomers of a chiral Price: $